Anti-aging formulation with stabiled Epigallo Catechin Gallate (ECGC)

ABSTRACT

The present invention provides for an anti-aging formulation comprising an elastomer, dispersant, active such as Epigallo Catechin Gallate (EGCG) and a drug and related methods of manufacture.

RELATED APPLICATION

This application is a continuation-in-part of U.S. patent Ser. No.14/756,288 filed on Aug. 21, 2015 entitled “Acne Formulation HavingStabilized Ascorbic Acid and Other Actives”, which is acontinuation-in-part of U.S. patent Ser. No. 13/999,696 filed on Mar.18, 2014 entitled “Delivery System Having Stabilized Ascorbic Acid andOther Actives” and issued as U.S. Pat. No. 9,144,564 and issued on Sep.29, 2015, which is a continuation-in-part of U.S. patent Ser. No.13/816,000 filed on Mar. 21, 2013 entitled “Delivery System HavingStabilized Ascorbic Acid and Other Actives” and issued as U.S. Pat. No.9,132,080 and issued on Sep. 15, 2015.

BACKGROUND OF INVENTION

Field of Invention

The present invention relates a delivery system with actives such asascorbic acid that retain their stability, functionality and aesthetics.In particular, a formulation and related method of manufacturecomprising: at least one elastomer; a first dispersant; a seconddispersant and at least one active wherein the formulation forms adelivery system wherein the active in the formulation retains itsstability, functionality and aesthetics.

Vitamin C, also known as L-ascorbic acid, has been known to be a veryimportant cosmetic active for a long time. It functions as ananti-oxidant, anti-inflammatory, a tyroinase inhibitor (blocking theproduction of melanin), and a collagen synthesis material. Thesemulti-functional benefits is the reason that vitamin C is so dearlydesired to be in cosmetic products. Unfortunately, it is also one of themost unstable materials as well. Vitamin C quickly degrades creatingcolor and odor issues making sale of products containing it notdesirable. The industry has created many derivatives to get around thisissue. They have not totally been successful either. Limitations onconcentration and aesthetics are still a big concern. That being saidthe most active for is the free L-ascorbic acid, which is stabilized inour composition.

Description of Related Art

The prior art shows that the most crucial problem with any water solubleantioxidant, such as ascorbic acid, is its stability in a formulation.In addition, these antioxidants or actives are crystalline or powder,and would feel like “sand” when formulated into a skin care or cosmeticproduct. Furthermore, the prior arts' teachings of incorporating theseactives into anhydrous systems do not solve the problem. The “feel” ofthe skin care or cosmetic products using the anhydrous system isundesirable.

The present invention provides for a delivery system wherein the watersoluble antioxidant retains its stability, functionality and aesthetics.

SUMMARY OF INVENTION

In one embodiment, the present invention provides for a formulationcomprising: at least one elastomer; a first dispersant; a seconddispersant and at least one active wherein the formulation forms adelivery system wherein the active in the formulation retains itsstability, functionality and aesthetics.

In another embodiment, the elastomer is selected from a group consistingessentially of Dimethicone/Dimethicone crosspolymers,Dimethicone/Vinyldimethicone crosspolymers, Silicone crosspolymers,Silicone, and combination and mixtures thereof. For purposes of thisinvention, the term “elastomer” is defined as any natural or syntheticmaterial, including polymers, that is able to resume its original shapewhen a deforming force is removed.

In yet another embodiment, the first dispersant is selected from a groupconsisting essentially of Cyclomethicone, Isododecane, Hydrocarbons,Esters, Dimethicones, petrolatum, Cyclopentasiloxane, and combinationand mixtures thereof.

In still another embodiment, the second dispersant is selected from agroup consisting essentially of Dimethicone, Cyclomethicones,Hydrocarbons, Esters, and combination and mixtures thereof. For purposesof this invention, the term “dispersant” is defined as a liquid or gasadded to a mixture to promote dispersion or maintain dispersed particlesin suspension and also includes any material that is able to gel theelastomer dispersed in it while keeping its structure and stability overtime.

In still yet another embodiment, the active is selected from a groupconsisting essentially of Ascorbic Acid, Epigallo Catechin Gallate(EGCG), Hydroquinone, Ubiquinone, Ubiquinol, Ferrulic Acid, Lipoic acid,and combination and mixtures thereof.

In a further embodiment, the formulation can be used as a productselected from a group consisting of skin care products, cosmetics,cosmeceuticals, pharmaceuticals and nutraceuticals. In another furtherembodiment, the formulation can be combined with other components andingredients to form a product selected from a group consisting of skincare products, cosmetics, cosmeceuticals, pharmaceuticals andnutraceuticals.

In yet a further embodiment, the formulation further comprises anactivator selected from a group consisting essentially of Water,Glycerin, Glycols, Polyols, Polyglutamic Acid, Hyaluronic Acid, andcombination and mixtures thereof.

In still a further embodiment, the formulation further comprises atleast one anhydrous system such as bentone cyclomethicone gel withorganic sunscreens. For purposes of this invention, the term “anhydrous”is defined as any non-aqueous (no water) or limited water containingformulation or composition.

In still yet a further embodiment, the second dispersant has a viscosityfrom about 0.65 to about 350 centistoke.

In another embodiment, the present invention provides for a formulationmanufactured by a process comprising: admixing at least one elastomerwith a first dispersant to form a gel; admixing a second dispersant withthe gel; and admixing at least one active with the gel to form adelivery system with an active in the formulation retains its stability,functionality and aesthetics.

In yet another further embodiment, the second dispersant has a viscosityfrom about 0.65 to about 20 centistoke.

In yet another further embodiment, the process further comprisesadmixing at least one sunscreen formulation.

In still another further embodiment, the present invention relates to aformulation containing ascorbic acid, and the formulation comprises: atleast one elastomer; a first dispersant; a silicone and ascorbic acidwherein the formulation forms a delivery system wherein the ascorbicacid in the formulation retains its stability, functionality andaesthetics.

In still yet another further embodiment, the present invention providesfor a formulation manufactured by a process comprising: admixing atleast one elastomer with a first dispersant to form a gel; admixing asilicone with the gel; and admixing ascorbic acid with the gel to form adelivery system with an active in the formulation retains its stability,functionality and aesthetics.

In another embodiment, the process further comprises admixing at leastone activator selected from a group consisting essentially of Water,Glycerin, Glycols, Polyols, Polyglutamic Acid, Hyaluronic Acid, andcombination and mixtures thereof.

In a further embodiment, the present invention relates to a formulationcomprising: at least one elastomer less than 50% of the formulation andat least one active from about 0.05 to about 50% of the formulation, andwherein the formulation forms a delivery system wherein said active insaid formulation retains its stability, functionality and aesthetics.

In another further embodiment, the present invention relates to aformulation comprising: at least one elastomer less than 50% of theformulation; a first dispersant from about 10 to about 90% of theformulation; a second dispersant from about 2 to about 40% of theformulation and at least one active from about 0.05 to about 50% of theformulation.

In yet another further embodiment, the present invention relates to aformulation comprising: at least one elastomer less than 50% of theformulation; a dispersant from about 10 to about 90% of the formulation;and at least one active from about 0.05 to about 50% of the formulation.

In another embodiment, the present invention relates to a formulationcomprising of: at least one elastomer selected from a group consistingof Dimethicone Copolymers in Dimethicone, Vinyldimethicone Copolymers inDimethicone, Dimethicone crosspolymers in Dimethicone, Vinyldimethiconecrosspolymers in Dimethicone, Silicone, and combination and mixturesthereof; at least one dispersant selected from a group consisting ofCyclomethicone, Isododecane, Hydrocarbons, Esters, Dimethicones,petrolatum, Cyclopentasiloxane, and combination and mixtures thereof; atleast one active selected from a group consisting of Ascorbic Acid,Epigallo Catechin Gallate (EGCG), Alpha Hydroxy Acids, Hydroquinone,Ubiquinone, Ubiquinol, Ferrulic Acid, Lipoic acid, and combination andmixtures thereof; and at least one drug selected from a group consistingof salicylic acid, benzoyl peroxide, sulfur, resorcinol, and resorcinolmonoacetate, and combinations and mixtures thereof.

In yet another embodiment, the formulation further comprises at leastone activator selected from a group consisting of Water, Glycerin,Glycols, Polyols, Polyglutamic Acid, Hyaluronic Acid, and combinationand mixtures thereof.

In still another embodiment, the formulation further comprisespreservatives, said preservatives being selected from a group consistingof phenoxyethanol, sodium benzoate, sorbic acid, alcohol, carpyl glycol,methylparaben, butyl paraben, propylparaben, ethylparaben,heptylparaben, and combination and mixtures thereof.

In still yet another embodiment, the formulation is designed fortreatment of acne. In a further embodiment, the drug is anover-the-counter drug.

In yet a further embodiment, the elastomer is from about 5% to about 90%of the formulation; the dispersant is from about 1% to about 40% of theformulation; active is from about 0.1% to about 40% of the formulation;drug is from about 0.5% to about 10% of the formulation; activator isfrom about 1% to about 50% of said formulation; and the preservative isfrom about 0.1% to about 5% of the formulation.

In another further embodiment, the present invention provides for aprocess for manufacturing a formulation, and the process comprises:admixing at least one elastomer with at least one dispersant to form agel, and the elastomer is selected from a group consisting ofDimethicone Copolymers in Dimethicone, Vinyldimethicone Copolymers inDimethicone, Dimethicone crosspolymers in Dimethicone, Vinyldimethiconecrosspolymers in Dimethicone, Silicone, and combination and mixturesthereof, the first dispersant is selected from a group consisting ofCyclomethicone, Isododecane, Hydrocarbons, Esters, Dimethicones,petrolatum, Cyclopentasiloxane, and combination and mixtures thereof;admixing at least one active with the gel to form a delivery systemwherein the active in the formulation retains its stability,functionality and aesthetics, the active is selected from a groupconsisting of Ascorbic Acid, Epigallo Catechin Gallate (EGCG), AlphaHydroxy Acids, Hydroquinone, Ubiquinone, Ubiquinol, Feuulic Acid, Lipoicacid, and combination and mixtures thereof and admixing at least onedrug, and the drug selected from a group consisting of salicylic acid,benzoyl peroxide, sulfur, resorcinol, resorcinol monoacetate, andcombinations and mixtures thereof to thereby form a formulation with adelivery system.

In another embodiment, the process further comprises admixing at leastone activator selected from a group consisting of Water, Glycerin,Glycols, Polyols, Polyglutamic Acid, Hyaluronic Acid, and combinationand mixtures thereof.

In yet another embodiment, the process further comprises admixing atleast one preservative, and the preservatives are selected from a groupconsisting of phenoxyethanol, sodium benzoate, sorbic acid, alcohol,carpyl glycol, methylparaben, butyl paraben, propylparaben,ethylparaben, heptylparaben, and combination and mixtures thereof.

In still another embodiment, the present invention relates to an acnetreatment formulation comprising of: at least one elastomer selectedfrom a group consisting of Dimethicone Copolymers in Dimethicone,Vinyldimethicone Copolymers in Dimethicone, Dimethicone crosspolymers inDimethicone, Vinyldimethicone crosspolymers in Dimethicone, Silicone,and combination and mixtures thereof; at least one dispersant selectedfrom a group consisting of Cyclomethicone, Isododecane, Hydrocarbons,Esters, Dimethicones, petrolatum, Cyclopentasiloxane, and combinationand mixtures thereof; at least one active selected from a groupconsisting of Ascorbic Acid, Epigallo Catechin Gallate (EGCG), AlphaHydroxy Acids, Hydroquinone, Ubiquinone, Ubiquinol, Ferrulic Acid,Lipoic acid, and combination and mixtures thereof; and at least one drugselected from a group consisting of salicylic acid, benzoyl peroxide,sulfur, resorcinol, and resorcinol monoacetate, and combinations andmixtures thereof, wherein said formulation is designed for treatment ofacne.

In another further embodiment, the active is Epigallo Catechin Gallate(EGCG). In still another embodiment, the present inventions relates to aformula wherein the collagen building actives are selected from thefollowing group and percent ranges of the entire formulation comprising:Vitamin A (Retinol) from about 0.05% to 2.0%, Vitamin B3 (Nyacinamide)from about 0.05% to about 5.0%, and Firulic Acid from about 0.01% toabout 5.0%, and combinations and mixtures thereof.

DETAILED DESCRIPTION OF THE INVENTION

As required, detailed embodiments of the present invention are disclosedherein; it is to be understood that the disclosed embodiments are merelyexemplary of the invention that may be embodied in various forms.Therefore, specific structural and functional details disclosed hereinare not to be interpreted as limits, but merely as a basis for teachingone skilled in the art to employ the present invention. The specificexamples below will enable the invention to be better understood.However, they are given merely by way of guidance and do not imply anylimitation.

In one embodiment, the focus of the present invention is stabilizing,inherently, unstable water-soluble anti-oxidants or actives such asAscorbic Acid (AA), Epigallocatechin Gallate (EGCG), and N-acetylglucosamine (NAG). These actives help to protect the skin when appliedtopically, by reducing the action of free radicals that can cause harmto cells. When the molecules are dissolved in water they also are opento oxidation, before they can be applied to skin. When the molecules arein their slid form, they are very stable. One option is to dispersethese actives in an essentially anhydrous vehicle, however, the endproduct is not aesthetically viable for commercial purposes. The activesare crystalline or powder, and would feel like “sand” when formulatedinto a skin care or cosmetic product and therefore, undesirable toconsumers.

In another embodiment, the present invention provides for a solutionusing gels. The selection of the gelling agent is critical. If thevehicle is too thin, the materials will sink to the bottom and theformula will not be homogeneous, and will not be able to deliver properdoses to the skin. If the vehicle is too thick, it will not apply evenlyand the consumer/end user will not like the “feel”.

In a further embodiment, using a gel having a cream-like consistency isoptimal. It allows the consumer to apply and enjoy the comfort andbenefit of the therapy. In another embodiment, the presently claimedinvention uses Elastomer technology to achieve the desired results.Dimethicon/vinyldimethicone crosspolymers have been used in cosmetics tocreate great texture and feel. Interestingly, when one of thesemolecules is added to the different elastomer gels, the combination isstable but is aesthetically undesirable because you can feel thescratchiness of the dispersed materials. Therefore the right dispersingagents must be used to not only gel the elastomer, but to enable theactive materials to blend into the base homogeneously.

The present invention has shown that using Isododecane andCyclopetasiloxane, and Dimeticone 5 cps provides for desired results.Although we recognize that there are other materials that could have asimilar effect, to achieve the overall viscosity and texture for afinished formulation that has extraordinary aesthetics a seconddispersant is used to fine tune the right consistency. Elastomers aresilicone rubbers that have been used in many industries. The finishedformula we have is cosmetically commercial and viable. It efficientlystabilizes the actives until they reach the skin. The water proof filmthat is left on the skin after it is applied, not only is silky smoothand desirable but helps to aid the penetration and keep the active inplace, until it can be absorbed.

The following examples are set forth below:

Example 1 Vitamin C Formulation

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. Theingredients and % of each ingredient in the composition is set forthbelow in Table 1.

TABLE 1 Phase: Ingredients: INCI % A IDS-5 Cyclopentasiloxane & 65.00Polysilicone-11 & Isododecane B DC 200 5 cst Dimethicone 15.00 C VitaminC Ascorbic Acid 20.00 100.00

Example 2 Vitamin C, N-Acetyl D-Glucosamine & Green Tea ExtractFormulation

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. Theingredients and % of each ingredient in the composition is set forthbelow in Table 2.

TABLE 2 Phase: Ingredients: INCI % A IDS-5 Cyclopentasiloxane & 59.00Polysilicone-11 B DC 200 5 cst Dimethicone 15.00 C Vitamin C AscorbicAcid 20.00 N-Acetyl D-Glucosamine N-Acetyl D-Glucosamine 5.00 Green TeaExtract Epigallo Catechin Gallate 1.00 (EGCG) 100.00

Example 3 Green Tea Extract Formulation

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. Theingredients and % of each ingredient in the composition is set forthbelow in Table 3.

TABLE 3 Phase: Ingredients: INCI % A IDS-5 Cyclopentasiloxane & 93.00Polysilicone-11 B DC 200 5 cst Dimethicone 5.00 C Green Tea ExtractEpigallo Catechin Gallate 2.00 (EGCG) 100.00

Example 4 N-Acetyl D-Glucosamine Formulation

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. Theingredients and % of each ingredient in the composition is set forthbelow in Table 4.

TABLE 4 Phase: Ingredients: INCI % A IDS-5 Cyclopentasiloxane & 82.00Polysilicone-11 B DC 200 5 cst Dimethicone 10.00 C N-AcetylD-Glucosamine N-Acetyl D-Glucosamine 8.00 100.00

Example 5 Vitamin C Formulation

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. GransilGVL is 85% Coconut Alkanes and 15% Polysilicone-11, there is 24.75%total Silicone in the formulation. The ingredients and % of eachingredient in the composition is set forth below in Table 5.

TABLE 5 Phase: Ingredients: INCI % A Gransil GVL Coconut Alkanes &Polysilicone-11 65.00 B DC 200 5 cst Dimethicone 15.00 C Vitamin CAscorbic Acid 20.00 100.00

Example 6 Vitamin C Formulation

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. PC-12 is85% Isododecane and 15% Polysilicone-11, there is 24.75% total Siliconein the formulation. The ingredients and % of each ingredient in thecomposition is set forth below in Table 6.

TABLE 6 Phase: Ingredients: INCI % A PC - 12 Isododecane &Polysilicone-11 65.00 B DC 200 5 cst Dimethicone 15.00 C Vitamin CAscorbic Acid 20.00 100.00

Example 7 Vitamin C, N-Acetyl D-Glucosamine & Green Tea ExtractFormulation

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. GransilGVL is 85% Coconut Alkanes and 15% Polysilicone-11, there is 23.8% totalSilicone in the formulation. The ingredients and % of each ingredient inthe composition is set forth below in Table 7.

TABLE 7 Phase: Ingredients: INCI % A Gransil GVL Coconut Alkanes & Poly-59.00 silicone-11 B DC 200 5 cst Dimethicone 15.00 C Vitamin C AscorbicAcid 20.00 N-Acetyl N-Acetyl D-Glucosamine 5.00 D-Glucosamine Green TeaExtract Epigallo Catechin Gallate 1.00 (EGCG) 100.00

Example 8 Vitamin C, N-Acetyl D-Glucosamine & Green Tea ExtractFormulation

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. PC-12 is85% Isododecane and 15% Polysilicone-11, there is 23.8% total Siliconein the formulation. The ingredients and % of each ingredient in thecomposition is set forth below in Table 8.

TABLE 8 Phase: Ingredients: INCI % A PC - 12 Isododecane &Polysilicone-11 59.00 B DC 200 5 cst Dimethicone 15.00 C Vitamin CAscorbic Acid 20.00 N-Acetyl N-Acetyl D-Glucosamine 5.00 D-GlucosamineGreen Tea Extract Epigallo Catechin Gallate 1.00 (EGCG) 100.00

Example 9 Green Tea Extract Formulation

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. GransilGVL is 85% Coconut Alkanes and 15% Polysilicone-11, there is 18.95%total Silicone in the formulation. The ingredients and % of eachingredient in the composition is set forth below in Table 9.

TABLE 9 Phase: Ingredients: INCI % A Gransil GVL Coconut Alkanes & Poly-93.00 silicone-11 B DC 200 5 cst Dimethicone 5.00 C Green Tea ExtractEpigallo Catechin Gallate (EGCG) 2.00 100.00

Example 10 Green Tea Extract Formulation

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. PC-12 is85% Isododecane and 15% Polysilicone-11, there is 18.95% total Siliconein the formulation. The ingredients and % of each ingredient in thecomposition is set forth below in Table 10.

TABLE 10 Phase: Ingredients: INCI % A PC - 12 Isododecane &Polysilicone-11 93.00 B DC 200 5 cst Dimethicone 5.00 C Green TeaExtract Epigallo Catechin Gallate (EGCG) 2.00 100.00

Stability tests were also conducted over a six month period and thetests results showed no deterioration of the actives. The stabilitytests are set for the below in Table 11:

ICC STABILIZED ACTIVE STABILITY DATA Initial 24 Hour Month 1 Month 2Month 3 Month 6 CONTROL VITAMIN C 25° C. Water White Water white YellowDk. Yellow/OJ Dk. Yellow/OJ Dk. Yellow/OJ 50° C. Water White Sl. YellowDk. Yellow Deep Orange Deep Orange Deep Orange VITAMIN C J116.01 25° C.White Cream White Cream White Cream White Cream White Cream White Cream50° C. White Cream White Cream White Cream White Cream White Cream WhiteCream Vitamin C Anhydrous System J116.02 25° C. Sl. Pink Beige Sl. PinkBeige Sl. Pink Beige Sl. Pink Beige Sl. Pink Beige Sl. Pink Beige 50° C.Sl. Pink Beige Sl. Pink Beige Sl. Pink Beige Sl. Pink Beige Sl. PinkBeige Sl. Pink Beige CONTROL EGCG 25° C. Slight Brown Slight Brown DarkBrown Dark Brown/Red Dark Brown/Red Dark Brown/Red 50° C. Slight BrownDk. Brown Dark Brown/Red Dark Brown/Red Dark Brown/Red Dark Brown/RedEGCG Anhydrous System J116.03 25° C. Sl. Pink Beige Sl. Pink Beige Sl.Pink Beige Sl. Pink Beige Sl. Pink Beige Sl. Pink Beige 50° C. Sl. PinkBeige Sl. Pink Beige Sl. Pink Beige Sl. Pink Beige Sl. Pink Beige Sl.Pink Beige N-Acetyl D-Glucosamine Anhydrous System J116.04 25° C. WhiteCream White Cream White Cream White Cream White Cream White Cream 50° C.White Cream White Cream White Cream White Cream White Cream White Cream*Color Only due to natural coloration to EGCG and indicates nodegredation or discoloration of formula

Example 11 Acne Formulation 1

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. TheGransil GVL is 83.5% Coconut Alkaines and Polysilicone-11, there is 15%Dimethicone, and there is 1.5% total Salicylic Acid in the formulation.The ingredients and % of each ingredient in the composition is set forthbelow in Table 11.

TABLE 11 Phase: Ingredients: INCI % A Grancil GVL Isododecane &Polysilicone-11 83.50 B DC 200 5 cst Dimethicone 15.00 C Salicylic AcidSalicylic Acid 1.50 100.00

Example 12 Acne Formulation 2

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. Phase Dis then slowly admixed with Phase ABC and mixed on very high speed. TheGransil GVL is 82% Coconut Alkaines and Polysilicone-11, there is 13%Dimethicone, and there is 3% total Sulfer and 2% Resorcinol in theformulation. The ingredients and % of each ingredient in the compositionis set forth below in Table 12.

TABLE 12 Phase: Ingredients: INCI % A Grancil GVL Isododecane &Polysilicone-11 82.00 B DC 200 5 cst Dimethicone 13.00 C Sulfer Sulfer3.00 D Resorcinol Resorcinol 2.00 100.00

Example 13 Acne Formulation 3

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. Phase Dis then slowly admixed with Phase ABC and mixed on very high speed. TheGransil GVL is 82% Coconut Alkaines and Polysilicone-11, there is 12%Dimethicone, and there is 3% total Sulfer and 3% Resorcinol Monoacetatein the formulation. The ingredients and % of each ingredient in thecomposition is set forth below in Table 13.

TABLE 13 Phase: Ingredients: INCI % A Grancil GVL Isododecane &Polysilicone-11 82.00 B DC 200 5 cst Dimethicone 12.00 C Sulfer Sulfer3.00 D Resorcinol Resorcinol MonoAcetate 3.00 MonoAcetate 100.00

Example 14 Anti-Aging Pure Vitamin C Formula 1

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. Phase Dis then slowly admixed with Phase ABC and mixed on very high speed. Theingredients and % of each ingredient in the composition is set forthbelow in Table 14.

TABLE 14 Phase: Ingredients: INCI % A Gransil GVL Coconut Alkanes &Poly- 64.9% silicone-11 B DC 200 5 cst Dimethicone 15% C Vitamin CAscorbic Acid 20% D Centella Asiatica Centella Asiatica Extract .01%100%

Example 15 Anti-Aging Pure Vitamin C Formula 2

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. Phase Dis then slowly admixed with Phase ABC and mixed on very high speed. Theingredients and % of each ingredient in the composition is set forthbelow in Table 15.

TABLE 15 Phase: Ingredients: INCI % A Gransil GVL Coconut Alkanes &Poly- 64.9% silicone-11 B DC 200 5 cst Dimethicone 15% C Vitamin CAscorbic Acid 20% D Green Tea Extract Epigallocatechin gallate .01% 100%

Example 16 Anti-Aging Pure Vitamin C Formula 2

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. Phase Dis then slowly admixed with Phase ABC and mixed on very high speed. Theingredients and % of each ingredient in the composition is set forthbelow in Table 16.

TABLE 16 Phase: Ingredients: INCI % A Gransil GVL Coconut Alkanes &Poly- 64.9% silicone-11 B DC 200 5 cst Dimethicone 15% C Vitamin CAscorbic Acid 20% D Green Tea Extract Epigallocatechin gallate .01% 100%

Example 17 Vitamin C Formulation

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. Phase Dis then slowly admixed with Phase ABC and mixed on very high speed. Theingredients and % of each ingredient in the composition is set forthbelow in Table 17.

TABLE 17 Phase: Ingredients: INCI % A Gransil GVL Coconut Alkanes &Poly- 64.00 silicone-11 B DC 200 5 cst Dimethicone 15.00 C Vitamin CAscorbic Acid 20.00 D Green Tea Extract Epigallocatechin gallate 1.00100%

Example 18 Vitamin C Formulation

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. Theingredients and % of each ingredient in the composition is set forthbelow in Table 18.

TABLE 18 Phase: Ingredients: INCI % A PC - 12 Isododecane &Polysilicone-11 59.00 B DC 200 5 cst Dimethicone 15.00 C Vitamin CAscorbic Acid 20.00 N-Acetyl N-Acetyl D-Glucosamine 5.00 D-GlucosamineGreen Tea Extract Epigallocatechin gallate 1.00 100%

Example 19 Vitamin C Formulation

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. Theingredients and % of each ingredient in the composition is set forthbelow in Table 19.

TABLE 19 Phase: Ingredients: INCI % A Gransil GVL Coconut Alkanes &Poly- 59.00 silicone-11 B DC 200 5 cst Dimethicone 15.00 C Vitamin CAscorbic Acid 20.00 N-Acetyl D-Glucosamine N-Acetyl D-Glucosamine 5.00Green Tea Extract Epigallocatechin gallate 1.00 100%

Example 20 Vitamin C Formulation

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. Theingredients and % of each ingredient in the composition is set forthbelow in Table 20.

TABLE 20 Phase: Ingredients: INCI % A Gransil GVL Coconut Alkanes &Poly- 65.00 silicone-11 B DC 200 5 cst Dimethicone 15.00 C Vitamin CAscorbic Acid 20.00 100%

Example 21 Vitamin C Formulation

Phase A is weighed in kettle equipped with a high speed agitation. PhaseB is then added to Phase A and mixed until homogeneous. Phase C is thenslowly admixed with Phase AB and then mixed on very high speed. Phase Dis then slowly admixed with Phase ABC and mixed on very high speed. Theingredients and % of each ingredient in the composition is set forthbelow in Table 21.

TABLE 21 Phase: Ingredients: INCI % A Gransil GVL Coconut Alkanes &Poly- 64.90 silicone-11 B DC 200 5 cst Dimethicone 15.00 C Vitamin CAscorbic Acid 20.00 D Centella Asiatica Centell Asiatica Extract 00.10100%

The present invention is not limited to the above Examples and Tables.Numerous modifications and variations of the present invention arepossible in light of the above teachings. It is therefore to beunderstood that within the scope of the attendant claims attachedhereto, this invention may be practiced other than as specificallydisclosed herein.

What is claimed is:
 1. A formulation comprising of: at least oneelastomer selected from a group consisting of Dimethicone Copolymers inDimethicone, Vinyldimethicone Copolymers in Dimethicone, Dimethiconecrosspolymers in Dimethicone, Vinyldimethicone crosspolymers inDimethicone, Silicone, and combination and mixtures thereof; at leastone dispersant selected from a group consisting of Cyclomethicone,Isododecane, Hydrocarbons, Esters, Dimethicones, petrolatum,Cyclopentasiloxane, and combination and mixtures thereof; at least oneactive selected from a group consisting of Epigallo Catechin Gallate(EGCG) and at least one collagen building active selected from a groupconsisting of scentella asiatica, peptides, proteins and tissue growthfactor (TGF)-Beta, natural extracts, glucosamine, Resvertrol, Vitamin A,Vitamin B3, Firulic Acid, and derivatives, combinations and mixturesthereof.
 2. The formulation of claim 1 further comprising at least oneactivator selected from a group consisting of Water, Glycerin, Glycols,Polyols, Polyglutamic Acid, Hyaluronic Acid, and combination andmixtures thereof.
 3. The formulation of claim 1 further comprisingpreservatives, said preservatives being selected from a group consistingof phenoxyethanol, sodium benzoate, sorbic acid, alcohol, carpyl glycol,methylparaben, butyl paraben, propylparaben, ethylparaben,heptylparaben, and combination and mixtures thereof.
 4. The formulationof claim 1 wherein said formulation is designed to function as ananti-aging formulation.
 5. The formulation of claim 1 wherein saidelastomer is from about 5% to about 90% of said formulation.
 6. Theformulation of claim 1 wherein said dispersant is from about 1% to about40% of said formulation.
 7. The formulation of claim 1 wherein saidactive is from about 0.1% to about 40% of said formulation.
 8. Theformulation of claim 1 wherein said collagen building active is fromabout 0.0001% to about 40% of said formulation.
 9. The formulation ofclaim 2 wherein said activator is from about 1% to about 50% of saidformulation.
 10. The formulation of claim 3 wherein said preservative isfrom about 0.1% to about 5% of said formulation.
 11. A process formanufacturing a formulation, said process comprising: admixing at leastone elastomer with at least one dispersant to form a gel, said elastomeris selected from a group consisting of Dimethicone Copolymers inDimethicone, Vinyldimethicone Copolymers in Dimethicone, Dimethiconecrosspolymers in Dimethicone, Vinyldimethicone crosspolymers inDimethicone, Silicone, and combination and mixtures thereof, said firstdispersant is selected from a group consisting of Cyclomethicone,Isododecane, Hydrocarbons, Esters, Dimethicones, petrolatum,Cyclopentasiloxane, and combination and mixtures thereof; admixing atleast one active with said gel to form a delivery system wherein saidactive in said formulation retains its stability, functionality andaesthetics, said active is Epigallo Catechin Gallate (EGCG); andadmixing at least one collagen building active selected from a groupconsisting of scentella asiatica, peptides, proteins and tissue growthfactor (TGF)-Beta, natural extracts, glucosamine, Resvertrol, Vitamin A,Vitamin B3, Firulic Acid, and combinations and mixtures thereof, tothereby form a formulation with a delivery system.
 12. The process ofclaim 11 further comprising admixing at least one activator selectedfrom a group consisting of Water, Glycerin, Glycols, Polyols,Polyglutamic Acid, Hyaluronic Acid, and combination and mixturesthereof.
 13. The process of claim 11 further comprising admixing atleast one preservative, said preservatives being selected from a groupconsisting of phenoxyethanol, sodium benzoate, sorbic acid, alcohol,carpyl glycol, methylparaben, butyl paraben, propylparaben,ethylparaben, heptylparaben, and combination and mixtures thereof. 14.The process of claim 11 wherein said formulation is designed to functionas an anti-agenting formulation.
 15. An anti-aging formulationcomprising of: at least one elastomer selected from a group consistingof Dimethicone Copolymers in Dimethicone, Vinyldimethicone Copolymers inDimethicone, Dimethicone crosspolymers in Dimethicone, Vinyldimethiconecrosspolymers in Dimethicone, Silicone, and combination and mixturesthereof; at least one dispersant selected from a group consisting ofCyclomethicone, Isododecane, Hydrocarbons, Esters, Dimethicones,petrolatum, Cyclopentasiloxane, and combination and mixtures thereof; atleast one active is Epigallo Catechin Gallate (EGCG); and at least onecollagen building active selected from a group consisting of scentellaasiatica, peptides, proteins and tissue growth factor (TGF)-Beta,natural extracts, glucosamine, Resvertrol, Vitamin A, Vitamin B3,Firulic Acid, and combinations and mixtures thereof.
 16. The formulationof claim 15 further comprising at least one activator selected from agroup consisting of Water, Glycerin, Glycols, Polyols, PolyglutamicAcid, Hyaluronic Acid, and combination and mixtures thereof.
 17. Theformulation of claim 15 further comprising preservatives, saidpreservatives being selected from a group consisting of phenoxyethanol,sodium benzoate, sorbic acid, alcohol, carpyl glycol, methylparaben,butyl paraben, propylparaben, ethylparaben, heptylparaben, andcombination and mixtures thereof.
 18. The formulation of claim 15wherein said elastomer is from about 5% to about 90% of saidformulation, said dispersant is from about 1% to about 40% of saidformulation, said active is from about 0.1% to about 40% of saidformulation, and said collagen building active is from about 0.00001% toabout 40% of said formulation.
 19. A method of manufacturing aformulation, said process comprising: admixing at least one elastomerwith at least one dispersant to form a gel, said elastomer is selectedfrom a group consisting of Dimethicone Copolymers in Dimethicone,Vinyldimethicone Copolymers in Dimethicone, Dimethicone crosspolymers inDimethicone, Vinyldimethicone crosspolymers in Dimethicone, Silicone,and combination and mixtures thereof, said first dispersant is selectedfrom a group consisting of Cyclomethicone, Isododecane, Hydrocarbons,Esters, Dimethicones, petrolatum, Cyclopentasiloxane, and combinationand mixtures thereof; admixing at least one active with said gel to forma delivery system wherein said active in said formulation retains itsstability, functionality and aesthetics, said active is EpigalloCatechin Gallate (EGCG); and admixing at least one collagen buildingactive selected from a group consisting of scentella asiatica, peptides,proteins and tissue growth factor (TGF)-Beta, natural extracts,glucosamine, Resvertrol, Vitamin A, Vitamin B3, Firulic Acid, andcombinations and mixtures thereof to thereby form a formulation with adelivery system.
 20. The method of claim 19 wherein said formulation isdesigned to be an anti-aging formulation.